Faculty & Research

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  • John Essigmann

    William R. (1956) & Betsy P. Leitch Professor in Residence Professor of Chemistry, Toxicology, and Biological Engineering
    Short Bio

    John Essigmann is the William R. (1956) and Betsy P. Leitch Professor in Residence of Chemistry in the MIT Department of Chemistry and Professor of Toxicology and Biological Engineering in the MIT Department of Biological Engineering. He was the Associate Head of the Department of Chemistry until 2012, responsible for graduate and undergraduate education, and from 2012 until 2019 he was the Director of the MIT Center for Environmental Health Sciences.  John was brought up in Medford, MA, a suburb of Boston and is a lifelong resident of the Boston area.

  • Bevin Engelward

    Professor of Biological Engineering; Director of the MIT Superfund Research Center
    Short Bio

    Major goals of the Engelward laboratory are to contribute to our understanding of factors that impact genomic stability through basic research, and through the development and application of novel technologies.

    • Develop mouse models for fluorescent detection of rare genetic changes
    • Reveal the impact of genes, environment, and physiological conditions on genomic stability
    • Create a high-throughput platform for measuring DNA damage in human cells
    • Apply high throughput technology for epidemiology and drug development
    • Explore the interfaces among DNA damage, repair, and infection
  • Cathy Drennan

    Professor of Chemistry and Biology; Investigator and Professor, Howard Hughes Medical Institute; MacVicar Faculty Fellow
    Short Bio

    The Drennan Research Laboratory seeks to understand how Nature harnesses and re-directs the reactivity of enzyme metallocenters in order to perform challenging reactions. The Drennan Lab Educational Initiatives focus on the development of resources for undergraduate science teaching and for the training of science educators.

  • Peter Dedon

    Underwood-Prescott Professor of Biological Engineering
    Short Bio

    Research in the Dedon Lab focuses on the chemical biology of nucleic acids in three broad areas: epigenetics, epitranscriptomics, and genetic toxicology.

  • Joey Davis

    Associate Professor of Biology
    Short Bio

    Having worked in Bob Sauer’s group as a Ph.D. student, I was thrilled to have the opportunity to return to MIT to start my lab. After graduating, I was the first employee at Ginkgo BioWorks, a local synthetic biology startup company and later was a post-doc in San Diego where I was jointly advised by Jamie Williamson and Malene Hansen. I’m excited to be back in Boston and working on key problems at the intersection of biochemistry, structural biology, and macromolecular complex assembly!

  • Otto Cordero

    Associate Professor CEE; Co-Director MIT Microbiology PhD Program
    Short Bio

    Professor Cordero studies the ecology and evolution of natural microbial collectives. His lab is interested in understanding how social and ecological interactions at micro-scales impact the global productivity, stability and evolutionary dynamics of microbial ecosystems.

  • James Collins

    Termeer Professor of Bioengineering
    Short Bio

    We are employing engineering principles to model, design and build synthetic gene circuits and programmable cells, in order to create novel classes of diagnostics & therapeutics.  We are also using deep learning approaches to discover new genetic parts and enhance the synthetic biology design process.

    As part of the Antibiotics-AI Project, we are harnessing the power of artificial intelligence (AI) to discover novel classes of antibiotics and rapidly understand how they work. We are also using deep learning approaches for the de novo design of new antibiotics and the development of combination treatments.

     

  • Jianzhu Chen

    Ivan R. Cottrell Professor of Immunology, Singapore Research Professor
    Short Bio

    Our research seeks to fundamentally understand how immune cells respond to pathogens and cancer, and how their dysfunction contributes to diseases. Our long-term goal is to elucidate the underlying molecular mechanisms and use this understanding to develop better treatments for cancer and metabolic diseases and better vaccines for infection.

  • Cullen Buie

    Associate Professor of Mechanical Engineering
    Short Bio

    Cullen is currently an Associate Professor of Mechanical Engineering (with tenure) at MIT. His laboratory explores flow physics at the microscale for applications in materials science and microbiology. His research is applicable to a diverse array of problems, from anti-biofouling surfaces and biofuels to energy storage and bacterial infections. Cullen is the recipient of numerous awards for his research and service including the National Science Foundation CAREER Award (2012), the DuPont Young Professor Award (2013), the DARPA Young Faculty Award (2013), and the Presidential Early Career Award for Scientists and Engineers (2016). Cullen’s C.V. can be found here.

  • Bryan Bryson

    Phillip and Susan Ragon Career Development Professor
    Short Bio
    • Understanding and predicting the host and bacterial determinants of bacterial fate
    • Developing novel tools to interrogate bacterium:host interactions with single cell resolution
    • Reprogramming the innate immune system to improve bacterial control through systematic dissection of innate response pathways